The Houston Texans (5-5) are looking for revenge against the Indianapolis Colts (10-0) who barely beat them three weeks ago in Indianapolis.  The Texans should have sent that game into overtime if not for a missed field goal by their kicker Kris Brown with only seconds left.  The Texans will need a big game out of Matt Schaub if they want to win this one, and he needs to make sure he takes care of the ball like last week where he did not throw any interceptions.  It was the first time he did that since week two, and this will probably be another close game so they cannot afford any turnovers.  The running game has not been producing enough this year, and Steve Slaton is battling a neck injury, so that means even more pressure is on Schaub.

The Texans defense is going to have its hands full with Peyton Manning.  Manning has been great all season for the Colts, and this game will probably be no different.  Manning does have an injured glute though, so he may not be as effective as he usually is.  He will still be Peyton Manning though, and even without a good running game (only 85 rushing yards per game), Manning has lead the Colts this far without a loss.  It should be a close game, but I’m going to go with Manning and the Colts in this one.

FINAL SCORE PREDICTION:  Houston Texans 17, Indianapolis Colts 24